Intraepithelial carcinoma (Bowen disease) - Carcinoma Intraepithelial (Galar Bowen)
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Cùis àbhaisteach - dh’ fhaodadh Carcinoma Intraepithelial (Galar Bowen) (Intraepithelial carcinoma (Bowen disease)) a bhith air a mhì-bhreithneachadh mar eczema maireannach, neo-thasach.
References
Is e seòrsa de aillse craiceann a th’ ann an Bowen's disease (BD) a thòisicheas ann an sreath a-muigh a’ chraicinn (epidermis) . Tha e nas cumanta ann an Caucasians agus bidh e tric a 'tachairt ann an ceàrnaidhean a tha fosgailte do sholas na grèine, ach faodaidh e nochdadh ann an àiteachan eile cuideachd. Mar as trice bidh BD a’ nochdadh mar aon lesion. Tha BD gu tric air fhaicinn mar shoidhne rabhaidh mus tig seòrsa nas miosa de aillse craiceann air adhart. Gus BD a dhearbhadh, mar as trice bidh dotairean an urra ri bhith a’ sgrùdadh sampallan clò fo mhiocroscop (biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bidh Bowen's disease mar as trice a’ toirt buaidh air daoine geala nas sine na 60. Tha prìomh nithean cunnairt a’ toirt a-steach foillseachadh grèine fad-ùine, siostam dìon lag, foillseachadh arsainic, agus galar HPV craiceann. Tha gathan HPV 16, 18, 34, agus 48 ceangailte ri galar Bowen ann an raointean gnèitheach. Chan eil com-pàirt HPV ann an cùisean neo-ghinealach cho soilleir.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Mar as trice bidh e a 'nochdadh mar àite erythematous, sgàile no crùbach an àite sam bith air a' bhodhaig. Is e an suidheachadh as cumanta casan ìosal.
Faodar a leigheas le diofar roghainnean làimhseachaidh leithid cryotherapy, curettage, rabhadh, photodynamic therapy, no toirt air falbh an lesion.
○ Diagnosis agus Làimhseachadh
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy